profile picture of Matthias Koch
  • Assistant Professor
Research Areas
  • Cell, Molecular & Developmental
  • Genetics & Genomics
  • Microbiology

Biography

Joined the Department in 2022

Research Interests

Laboratory Details

Laboratory Address:
Biological Sciences Building West
Room 401

Educational Background

  • M.Sc., Physics, University of Freiburg. 2010
  • Ph.D., Biophysics. 2015
  • Postdoctoral research, Princeton University. 2015-2022

Selected Publications

    1. Hendrix, H, Itterbeek, A, Longin, H, Delanghe, L, Vriens, E, Vallino, M et al.. PlzR regulates type IV pili assembly in Pseudomonas aeruginosa via PilZ binding. Nat Commun. 2024;15 (1):8717. doi: 10.1038/s41467-024-52732-5. PubMed PMID:39379373 PubMed Central PMC11461919.
    2. Stenzel, T, Dziewulska, D, Łukaszuk, E, Custer, JM, De Koch, MD, Kraberger, S et al.. The pigeon circovirus evolution, epidemiology and interaction with the host immune system under One Loft Race rearing conditions. Sci Rep. 2024;14 (1):13815. doi: 10.1038/s41598-024-64587-3. PubMed PMID:38877168 PubMed Central PMC11178769.
    3. Kraberger, S, Serieys, LEK, Leighton, GRM, De Koch, MD, Munday, JS, Bishop, JM et al.. Two Lineages of Papillomaviruses Identified from Caracals (Caracal caracal) in South Africa. Viruses. 2024;16 (5):. doi: 10.3390/v16050701. PubMed PMID:38793583 PubMed Central PMC11125996.
    4. Shuppara, AM, Padron, GC, Sharma, A, Modi, Z, Koch, MD, Sanfilippo, JE et al.. Fluid flow overcomes antimicrobial resistance by boosting delivery. bioRxiv. 2024; :. doi: 10.1101/2024.05.08.591722. PubMed PMID:38766052 PubMed Central PMC11100760.
    5. Cibele, D, Moreira, I, Jacques Costa, L, Ricca Gonçalves, L, Koch, MDC. Green Colored Plasma in a Patient with Breast Cancer. Acta Med Port. 2024;37 (3):222-223. doi: 10.20344/amp.20909. PubMed PMID:38285972 .
    6. Schroven, K, Putzeys, L, Kerremans, A, Ceyssens, P-J, Vallino, M, Paeshuyse, J et al.. The phage-encoded PIT4 protein affects multiple two-component systems of Pseudomonas aeruginosa. Microbiol Spectr. 2023;11 (6):e0237223. doi: 10.1128/spectrum.02372-23. PubMed PMID:37962408 PubMed Central PMC10714779.
    7. Palalay, JS, Simsek, AN, Reed, JL, Koch, MD, Sabass, B, Sanfilippo, JE et al.. Shear force enhances adhesion of Pseudomonas aeruginosa by counteracting pilus-driven surface departure. Proc Natl Acad Sci U S A. 2023;120 (41):e2307718120. doi: 10.1073/pnas.2307718120. PubMed PMID:37788310 PubMed Central PMC10576114.
    8. Wang, B, Lin, AE, Yuan, J, Novak, KE, Koch, MD, Wingreen, NS et al.. Single-cell massively-parallel multiplexed microbial sequencing (M3-seq) identifies rare bacterial populations and profiles phage infection. Nat Microbiol. 2023;8 (10):1846-1862. doi: 10.1038/s41564-023-01462-3. PubMed PMID:37653008 PubMed Central PMC10522482.
    9. Han, E, Fei, C, Alert, R, Copenhagen, K, Koch, MD, Wingreen, NS et al.. Local polar order controls mechanical stress and triggers layer formation in developing Myxococcus xanthus colonies. ArXiv. 2023; :. . PubMed PMID:37576128 PubMed Central PMC10418523.
    10. Simsek, AN, Koch, MD, Sanfilippo, JE, Gitai, Z, Gompper, G, Sabass, B et al.. Type-IV pili tune an adhesion-migration trade-off during surface colonization of Pseudomonas aeruginosa. bioRxiv. 2023; :. doi: 10.1101/2023.05.09.538458. PubMed PMID:37215001 PubMed Central PMC10197611.
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